Science - Biological Sciences

  • Associate Professor
  • LIM, WHASUN
    Lab 분자발생학 및 세포신호전달연구실

Research Interest

Cell signaling, molecular development, molecular pharmacology, toxicology, reproductive medicine

Education

  • (Ph.D.) Department of Agricultural Biotechnology, Seoul National University
  • (B.S.) Department of Food and Nutrition, Sookmyung Women's University

Experience

  • 2022 - Present | Associate Professor, Department of Biological Sciences, Sungkyunkwan University
  • 2019 - 2021 | Assistant Professor, Department of Food and Nutrition, Kookmin University
  • 2017 - 2019 | Assistant Professor, Department of Biomedical Sciences, Catholic Kwandong University
  • 2013 - 2017 | Research Professor, Department of Biotechnology, Korea University

Journal Articles

  • (2024)  Relevance of the endoplasmic reticulum-mitochondria axis in cancer diagnosis and therapy.  EXPERIMENTAL AND MOLECULAR MEDICINE.  56,  1
  • (2024)  Fraxetin reduces endometriotic lesions through activation of ER stress, induction of mitochondria-mediated apoptosis, and generation of ROS.  PHYTOMEDICINE.  123,  .
  • (2024)  Mevinphos induces developmental defects via inflammation, apoptosis, and altered MAPK and Akt signaling pathways in zebrafish.  COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY.  275,  .
  • (2023)  Cypermethrin induces endoplasmic reticulum stress and autophagy, leads to testicular dysfunction.  SCIENCE OF THE TOTAL ENVIRONMENT.  902,  -
  • (2023)  Bensulide-induced oxidative stress causes developmental defects of cardiovascular system and liver in zebrafish (Danio rerio).  JOURNAL OF HAZARDOUS MATERIALS.  455,  -
  • (2023)  Terbutryn causes developmental toxicity in zebrafish (Danio rerio) via apoptosis and major organ malformation in the early stages of embryogenesis.  SCIENCE OF THE TOTAL ENVIRONMENT.  893,  -
  • (2023)  Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish.  ENVIRONMENT INTERNATIONAL.  176,  -
  • (2023)  Exposure to the herbicide fluridone induces cardiovascular toxicity in early developmental stages of zebrafish.  SCIENCE OF THE TOTAL ENVIRONMENT.  867,  -
  • (2023)  Oryzalin impairs maternal-fetal interaction during early pregnancy via ROS-mediated P38 MAPK/AKT and OXPHOS downregulation.  FOOD AND CHEMICAL TOXICOLOGY.  174,  .
  • (2023)  Triadimenol promotes the production of reactive oxygen species and apoptosis with cardiotoxicity and developmental abnormalities in zebrafish.  SCIENCE OF THE TOTAL ENVIRONMENT.  862,  .
  • (2023)  Developmental toxicity of prometryn induces mitochondrial dysfunction, oxidative stress, and failure of organogenesis in zebrafish (Danio rerio).  JOURNAL OF HAZARDOUS MATERIALS.  443,  PartA
  • (2023)  Oxamyl exerts developmental toxic effects in zebrafish by disrupting the mitochondrial electron transport chain and modulating PI3K/Akt and p38 Mapk signaling.  SCIENCE OF THE TOTAL ENVIRONMENT.  859,  -
  • (2023)  Ethalfluralin induces developmental toxicity in zebrafish via oxidative stress and inflammation.  SCIENCE OF THE TOTAL ENVIRONMENT.  854,  -
  • (2023)  Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs.  JOURNAL OF PINEAL RESEARCH.  74,  1
  • (2022)  Hesperidin Suppresses the Proliferation of Prostate Cancer Cells by Inducing Oxidative Stress and Disrupting Ca2+ Homeostasis.  ANTIOXIDANTS.  11,  9
  • (2022)  Ethalfluralin impairs implantation by aggravation of mitochondrial viability and function during early pregnancy.  ENVIRONMENTAL POLLUTION.  307,  -
  • (2022)  Dinitramine induces implantation failure by cell cycle arrest and mitochondrial dysfunction in porcine trophectoderm and luminal epithelial cells.  JOURNAL OF HAZARDOUS MATERIALS.  435,  -
  • (2022)  A Synbiotic Combination of Lactobacillus gasseri 505 and Cudrania tricuspidata Leaf Extract Prevents Stress-Induced Testicular Dysfunction in Mice.  FRONTIERS IN ENDOCRINOLOGY.  13,  -
  • (2022)  Alpinumisoflavone Disrupts Endoplasmic Reticulum and Mitochondria Leading to Apoptosis in Human Ovarian Cancer.  PHARMACEUTICS.  14,  3
  • (2022)  Aclonifen induces bovine mammary gland epithelial cell death by disrupting calcium homeostasis and inducing ROS production.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY.  181,  -

Patent/Intellectual Property

  • 스티그마스테롤을 유효성분으로 함유하는 난소암 예방 또는 치료용 조성물(COMPOSITION FOR PREVENTING OR TREATING OVARIAN CANCER COMPRISING STIGMASTEROL).  10-2580-9180000.  20230915.  KOREA, REPUBLIC OF
  • 크리소파놀을 포함하는 난소암 또는 유방암의 예방 또는 치료용 약학적 조성물(Pharmaceutical composition for preventing or treating ovarian cancer or breast cancer comprising chrysophanol).  10-2498-8000000.  20230207.  KOREA, REPUBLIC OF
  • 후코스테롤을 유효성분으로 함유하는 난소암 예방 또는 치료용 조성물(COMPOSITION FOR PREVENTING OR TREATING OVARIAN CANCER COMPRISING FUCOSTEROL).  10-2020-0042725.  20220310.  KOREA, REPUBLIC OF
  • 유파틸린을 유효성분으로 함유하는 난소암 예방 또는 치료용 조성물(COMPOSITION FOR PREVENTING OR TREATING OVARIAN CANCER COMPRISING EUPATILIN).  10-2020-0042724.  20220303.  KOREA, REPUBLIC OF